Substrate: Heme oxygenase 1 (signal transducer activity)
Seq-ID: P09601 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
heme binding,
enzyme binding,
signal transducer activity,
heme oxygenase (decyclizing) activity		 microsome,
extracellular space,
endoplasmic reticulum		 angiogenesis,
heme oxidation,
positive regulation of I-kappaB kinase/NF-kappaB cascade,
erythrocyte homeostasis,
oxidation reduction,
regulation of transcription from RNA polymerase II promoter in response to oxidative stress,
response to hydrogen peroxide,
heme catabolic process,
anti-apoptosis,
endothelial cell proliferation,
positive regulation of chemokine biosynthetic process,
positive regulation of smooth muscle cell proliferation,
excretion,
negative regulation of smooth muscle cell proliferation,
negative regulation of leukocyte migration,
wound healing involved in inflammatory response,
low-density lipoprotein particle clearance,
smooth muscle hyperplasia,
protein homooligomerization,
response to nicotine,
iron ion homeostasis,
intracellular protein kinase cascade,
cell death,
positive regulation of vasodilation,
regulation of angiogenesis
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 229 ELLTHDTKDQSPSRAPGLRQR - 17081983
HTP
0.05
 - -
0.71
 --
S 231 LTHDTKDQSPSRAPGLRQRAS - 17081983
HTP
0.13
 - -
0.75
 --

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